DYNAMIC SIZING OF CLOUD-NATIVE TELCO DATA CENTERS WITH DIGITAL TWIN AND REINFORCEMENT LEARNING



An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells.

Alterations in checkpoint and DNA repair pathways may provide adaptive mechanisms contributing to acquired drug resistance.Here, we Cooktop Bench Seal investigated the levels of proteins mediating DNA damage signaling and -repair in RPMI8226 multiple myeloma cells and its Melphalan-resistant derivative 8226-LR5.We observed markedly reduced steady-s

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